Nicotiana glauca is a species of tobacco known by the common name tree tobacco . Its leaves are attached to the stalk by petioles (many other Nicotiana species-have sessile leaves) and Its leaves and stems are Neither pubescent nor sticky like Nicotiana tabacum . It Resembles Cestrum parqui purpose differs in the form of leaves and floral fusion of the outer sides. It grows to heights of more than two meters.
Tree tobacco is native to South America purpose it is Now Widespread year have introduced species are other continents. It is a common roadside weed in the southwestern United States , and an invasive plant species in California native plant habitats .
The plant is used for a variety of medicinal purposes and smoked by Native American groups .  The Cahuilla Indians used interchangeably with other leaves in a variety of rituals and poultices to treat swellings, bruises, cuts, wounds, boils, sores, inflamed throat, and swollen acorns. Contains the toxic alkaloid anabasine . Ingestion of the leaves can be fatal.  It is being investigated for use as a biofuel . 
- Jump up^ “BRIT – Native American Ethnobotany Database” . herb.umd.umich.edu . Retrieved 2017-03-12 .
- Jump up^ Foster, Steven (2002). Western Medicinal Plants and Herbs . Boston, NY: Houghton Mifflin Company. p. 339. ISBN 0-395-83806-1 .
- Jump up^ Media, BioAge. “Green Car Congress: Prickly Pears and Tobacco Tree for Ethanol Production in Semi-Arid Regions” . www.greencarcongress.com . Retrieved 2017-03-12 .